PREP 2024

36th International Symposium on Preparative and Process Chromatography

 Philadelphia, PA, United States    May 28-31, 2024

Gold Sponsors

Bio-Rad Laboratories

Bio-Rad Laboratories is a leading provider in life science and clinical diagnostics markets, focusing on discovery, drug development, and biopharmaceutical production to advance science and save lives together. Bio-Rad’s long-lasting customer relationships foster the company's research and development efforts and inspire the introduction of innovative products and solutions that accelerate the discovery process and improve healthcare. The Process Chromatography Business, part of the Life Science Group at Bio-Rad, provides researchers with the chromatography tools they need to isolate and purify proteins from discovery through clinical trials into biomanufacturing. With more than 70 years of purification experience, Bio-Rad continues to expand solutions to streamline the drug discovery and development process.

Cytiva

Cytiva and Pall Life Sciences have come together to deliver the breadth, depth, and scale researchers and biopharma need to advance future therapeutics – from discovery to delivery. Together, as Cytiva, we supply the tools and support our customers need to work better, faster and safer, leading to the delivery of transformative medicines to patients. Our combined portfolio includes well-recognized names such as Allegro™, Supor™, iCELLis™, and Kleenpak™, in addition to ÄKTA™, Amersham™, Biacore™, FlexFactory™, HyClone™, MabSelect™, Sefia™, Whatman™, and Xcellerex™.

Shimadzu

The most important aspects of separation and purification are purity results, preparative processing speed, and cost-effectiveness. Shimadzu’s preparative system enhances all of these aspects in each scale-up process, offering high purity, high-speed preparation, and improved efficiency. A method scouting system enables efficient method development and significantly reduces the process for setting fractionation parameters while an LCMS prep system enables high-purity recovery of target components using multiple signal triggers. Multiple solvent delivery units, a liquid handler equipped with auto injection and fraction collection functions, and a versatile, efficient, easy-to-use fraction collector enable excellent system expandability.

 

Sunresin New Materials

Sunresin is an innovation oriented high-tech enterprise, specialized in supplying Ion exchange resins, adsorption & separation resins, equipment solutions and relevant technical services.

Sunresin focuses on innovation, quality and service. Based on the technical core competences, the rich experience and under strict international standards, providing high quality products, cost-effective equipment as well as professional design and solution to the customers.

Our vision is to empower Life Sciences customers with cutting-edge products and technologies able ultimately to transform people life.

Tosoh Bioscience LLC

The Separations and Purification group of Tosoh Bioscience, a division of Tosoh Corporation, is a major global supplier of chromatographic solutions predominately serving the pharmaceutical, biotechnology, and chemical industries.

Since 1987, our product portfolio has expanded and evolved to anticipate industry demands and exceed our customers’ needs. Our comprehensive line of analytical HPLC columns, bulk process media resins, and dedicated GPC systems for polymer analysis, coupled with our expertise, make the solution to your separation and purification process clear.

Silver Sponsors

Agilent Technologies

Agilent supports scientists in 110 countries in cutting-edge research; patient diagnostics; and testing required to ensure the safety of water, food and pharmaceuticals. Our advanced instruments, software, consumables, and services enable our customers to produce the most accurate and reliable results as well as optimal scientific, economic, and operational outcomes.

We play a role in advancing important research and testing, with our scientists creating some of the world's most leading-edge technology and our field engineers working side by side with customers to help them maximize productivity.

Together with our customers, we’re bringing great science to life.

Asahi Kasei Bioprocess America

The Fluid Management Business Unit of Asahi Kasei Bioprocess is devoted to solving therapeutic product safety, efficiency, and purity challenges within the pharmaceutical and bioprocessing industries. With technology platforms for oligonucleotide synthesis, buffer formulation, chromatography, and filtration, our bioprocess systems, columns, and automation solutions advance GMP manufacturing of critical drug substances around the world. Built with pride, built with quality, built to exceed expectations. "Built for You."

JNC Corporation

JNC prides itself as the distinguished manufacturer of Cellufine® — a premium line of cellulose-based chromatography media, masterfully engineered for the purification of proteins, enzymes, and a variety of biomolecules. The Cellufine line is well-regarded for its reliability and has been an integral part of numerous biopharmaceutical processes, earning the trust of industry professionals through its consistent performance and customer service over the years. We are excited to showcase our Cellufine collection alongside our cutting-edge MLP (Monolith Like Particle) technologies at the upcoming PREP conference.

Kromasil® by Nouryon

Kromasil is a high-performance chromatography media based on state-of-the-art spherical silica for analytical and industrial HPLC, SFC and SMB applications. Products are available in slurry-packed columns and in bulk for laboratory analyses and large-scale preparative purification. Kromasil silica-based packing materials offer large pore volume and surface area combined with excellent chemical and mechanical stability. Nouryon continues to be a world-class innovator delivering new platforms and tools for both slurry-packed columns and
bulk materials, pushing technological boundaries to exceed customers’ expectations. Kromasil is produced in Bohus, Sweden.

PIC Solution

PIC Solution is a global manufacturer of supercritical fluid technologies for eco-sustainable Supercritical Fluid Chromatography (SFC) and Extraction (SFE) with 20-years’ experience working with the pharmaceutical industry. PIC Solution provides state-of-the art equipment to do separations at the research, process, and industrial scale. Our newly developed Open-Bed SFC-MS instrument offers unique solutions for chiral and achiral separations in a high throughput mode while recycling CO2 to make this purification process greener. Our “One Machine – Multiple Use” instrument line combines analytical, preparative SFC and extraction on a single instrument. PIC Solution also offers services for custom purification and extraction.

SK Pharmteco

Headquartered in Rancho Cordova, Calif., SK pharmteco is a global contract development and manufacturing organization specializing in the production of active pharmaceutical ingredients (APIs), advanced intermediates, and cell and gene therapy for the pharmaceutical industry. SK pharmteco is comprised of six companies: SK Biotek Korea, SK Biotek Ireland, AMPAC Fine Chemicals, AMPAC Analytical Laboratories in the U.S., Yposkesi and the Center for Breakthrough Medicines. SK pharmteco is owned by SK Inc., the strategic investment arm of South Korea’s SK Group.

Thermo Fisher Scientific

Thermo Fisher Scientific is here to help guide the way forward in the new age of drug development. Because your success is our success, it’s our job to help accelerate your biomanufacturing process so you can deliver competitive results and commercialize innovative therapies that help improve health and quality of life. Improve your downstream process efficiency and productivity with a unique set of chromatography resins, pre-packed columns and purification solutions for even the most complex biomolecules.

YMC America

YMC is a premier full-spectrum liquid chromatography and downstream purification provider. We offer resins; prepacked capillary, analytical, and preparative columns; glass columns; DAC/DAD columns; and Contichrom® CUBE and TWIN LPLC and HPLC multi-column systems. A strong history of custom work has allowed YMC America to enhance its technology and develop a diverse platform of products and services that align with clients’ specific requirements. This allows customers to select the YMC products and optimized methodologies that result in maximum process efficiency. In addition, YMC America’s highly trained and knowledgeable technical staff partners with each customer supporting individualized needs for process optimizations.

Bronze Sponsors

Daicel Chiral Technologies

Daicel Chiral Technologies is a proven market leader in providing chiral chromatography solutions for optical isomer separation. We offer outstanding quality and performance that you can trust for your R&D and production needs. Separations of compounds are performed globally in our state-of-the-art facilities at scales ranging from milligrams to hundreds of kilograms to metric tons. Benefit from our complimentary compound screening, efficient project management and rapid turnaround times. We help our customers succeed with expert technical support, customer service, and scalable separation services.

DAISO Fine Chem USA Inc.

DAISOGEL is a leading bulk silica gel used in the chromatographic analysis and purification of active pharmaceutical ingredients and other high-value substances. It falls within the Pharmaceutical Related business of our parent company OSAKA SODA Co., Ltd.

Our products are manufactured under ISO 9001 controlled conditions using our leading-edge sol-gel method with GMP compliance based on ICH-Q7A.

Our superior manufacturing standards guarantee DAISOGEL is produced with the highest quality and purity to meet and exceed expectations of any major pharmaceutical company audit worldwide.

G-Flash, LLC

See innovative technology developed by G-Flash, LLC. GreenFlashchromatography (GFCTM) uses supercritical CO2 in place of the primary non-polar solvent typically used in flash, effectively eliminating 80% of the organic solvents required for traditional flash chromatography. Reducing solvent requirements saves money and time. Less time evaporating solvents means better workflow. The reduction in toxic, flammable solvents results in a safer work environment. Beyond traditional applications for small molecules, GFCTM has shown great potential to perform more difficult separations such as therapeutic peptides.

Itochu Chemicals America

ITOCHU Chemicals America, Inc. offers ion exchange resins, reverse phase polymeric beads, enzyme immobilization resins, and chromatography silica. Itochu provides purification solutions for small and large molecules, peptides, oligonucleotides, insulin analogs, precision fermentation-based compounds, CBD/THC, and food applications including dairy proteins, collagen, sweeteners, flavors, oils, and juices.

Knauer Wissenschaftliche Geräte GmbH

KNAUER manufactures in Berlin liquid chromatography instruments for research, routine analysis, quality assurance, and other applications. Apart from LC, KNAUER offers products for liquid handling, high-pressure dosing, flow-through detection, and more.

Customizable solutions are one of KNAUER's strengths. Latest example is the lipid nanoparticle production equipment used for mRNA vaccines.

Mitsubishi Chemical Corporation

Mitsubishi Chemical provides a wide variety of products, including separation materials, supporting the foundations of all types of industries. MCI GEL™ chromatography resins demonstrate high separation performance in the Downstream Processing in Biopharmaceuticals. Its high performance and quality are backed by more than 70 years of experience and technology in the manufacturing and development of DIAION™ ion exchange resins and SEPABEADS™ synthetic adsorbents.

Nanologica

Nanologica is a Swedish life science tools company that provides consumables to pharmaceutical manufacturers. Nanologica's silica-based products for preparative chromatography are specially developed for the purification of peptide drugs, such as insulin and GLP-1 analogues, and are manufactured using a proprietary production method. Due to effective purification and a long lifetime for the products, they can increase productivity and reduce costs for pharmaceutical manufacturers.

Nanologica's mission is to increase access to cost-effective drugs through its purification products, and thereby enable more patients around the world access to life-saving treatments for diabetes and obesity, for example.

NanoMicro Technologies

Established in Biobay, Suzhou in 2007, NanoMicro is the world leader in the manufacture of spherical, mono-disperse particles utilizing our proprietary manufacturing processes which enable high yield, cost effective production of such particles for a wide variety of industries and applications. NanoMicro's products cover a broad spectrum of applications including high performance chromatography media, solid phase extraction (SPE) sorbents, particle size standards, magnetic particles, LCD spacers, ACF conductive particles, and various other micro particles.

Our chromatography products are available in a variety of polymer formats with particle sizes from analytical through to preparative scale. Our proprietary expertise in controlling particle morphology and surface chemistry can be precisely tailored to optimize for solutes ranging from the smallest API to large constructs such as viruses and viral vectors. A wide range of surface chemistries is available from RPC/chiral for small molecules to ion exchange/affinity for biomolecules.

Separation Methods Technologies

Established in 1993, Separation Methods Technologies, Incorporated (SMT) is a pioneering surface chemistry research and manufacturing corporation. Our mission at SMT is to offer chromatographers exceptional specialty columns and bulk packing materials across a spectrum of separation chemistries, catering to applications from analytical to process scale. Our core expertise lies in the development of meticulously engineered functional molecules on substrate surfaces, serving diverse functions such as chromatographic applications and materials engineering.

Vendors

Advion Interchim Scientific

At Advion Interchim Scientific®, we deliver tailored solutions to improve our customers’ most challenging identification, quantification, and purification needs. Our unrivaled portfolio ranges from media and columns to consumables, accessories and instruments for flash chromatography, preparative and analytical (U)HPLC, mass spectrometry, ICP-MS, coupled with intelligent apps and software.

BUCHI

BUCHI is a leading global laboratory technology solutions provider for R&D, quality control, and production workplaces. We serve a wide range of industries including food and beverage, feed, environmental analysis, pharmaceuticals, and academia.  

Our solutions for rotary evaporation (industrial and benchtop), spray drying, melting point, flash chromatography, and freeze drying help customers simplify daily routines, improve workplace safety, reduce environmental impact, and enhance workflow efficiency.

ChromaTan, Inc

ChromaTan, a privately held bioprocessing and biotools company, has created a novel purification system called BioRMBTM (formerly known as Continuous Countercurrent Tangential Chromatography or CCTC). The platform has been launched in 2023, and has successfully demonstrated significant improvements in productivity, product recovery and product quality for multiple types of biologics including gene therapies, mRNA and monoclonal antibodies.  

Dr. Maisch HPLC GmbH

Dr. Maisch HPLC is a well-known manufacturer of LC columns with over 25 years’ experience in column packing. At the PREP Symposium we will introduce our patented prepacked preparative LONGLIFE hardware as well as our MODCOL Spring Column, enabling our customers to pack columns from 25 – 300 mm ID using dynamic axial compression technology. We will also present our portfolio of unique chiral and achiral stationary phases and columns including SFC columns.

emp Biotech

emp BIOTECH is a Berlin (Germany) based company specializing the development and manufacture of products for biomolecule purification, oligonucleotide synthesis and antibody/protein labeling – starting with early stage R&D applications and progressing through to full-scale cGMP manufacturing.

All products are manufactured at our production facilities in Germany and in accordance with ISO 9001:2015 and ISO 13485:2016 standards.

Gilson

We are Gilson, a third-generation family-owned company developing liquid handling, purification, and extraction solutions for the life science, pharmaceutical, and biotech industries. Since 1957, we have developed innovative solutions, designed to improve the reproducibility and traceability of data, connecting with the scientific community to help researchers achieve verifiable results. Since the introduction of the high-precision PIPETMAN® pipette, Gilson has revolutionized laboratories, providing a range of quality and innovative solutions including purification systems, solid phase extraction (SPE) systems, automated liquid handlers, pipettes & accessories. From Library Building to Production GMP & Non-GMP, Gilson provides the expertise, flexibility, and scalability you need.

LigaTrap Technologies

LigaTrap Technologies is an innovative North Carolina biotechnology company offering a unique suite of proprietary technologies used in the purification of proteins. We specialize in the purification of antibodies and viruses in the bioprocessing industry for antibody-based medications, viral vaccines, and gene therapy. Our portfolio includes LigaTrap’s novel LigaGuard technology, that is specially designed to purify host cell proteins from bioprocessing for mammalian samples and viruses, as well as our newly introduced AAVidity resin – that purifies Adeno-associated viruses from HEK293 and Sf9 lysate applications.

MAC-MOD Analytical

MAC-MOD supplies HPLC/UHPLC columns and accessories to all industries as well as now providing our NEW SPE products, and GC and Chiral GC columns.

We also offer safety caps which prevent hazardous materials from evaporating into your lab, keeping you safer.

Please contact us to learn more about our products and application guides or for questions about your toughest separations.  We look forward to speaking with you.

Purolite, An Ecolab Company

Purolite, An Ecolab Company is a leading manufacturer of quality affinity, ion exchange, adsorbent and specialty high-performance resins. Praesto™ bioprocessing products aim to improve the accessibility and availability of cutting-edge antibody therapeutics worldwide, which are typically used to treat, extend life, and improve quality of life for patients. These agarose-based chromatographic resins are key raw materials for the downstream processing of antibodies and recombinant proteins and are trusted by many of the leading biopharmaceutical manufacturers and CMOs. Praesto resins are currently implemented in FDA-approved commercial manufacturing processes and hundreds of clinical trials worldwide.

Sartorius

We at Sartorius support the biopharmaceutical and life science research industries to develop and manufacture medications from the first idea to production. We’re in this together. For better health for more people.

At Sartorius, we empower scientists and engineers to simplify and accelerate progress in life science and bioprocessing, enabling the development of new and better therapies and more affordable medicine.

Spark Holland

Spark Holland has over 40 years’ experience in the development of innovative and patented technology for sample preparation and liquid chromatography systems. We offer fully customizable, state-of-the art autosamplers, pumps and column ovens for the Life Science market, and now including technologies for preparative solutions as well. We are your full-service OEM partner.

Teledyne LABS

Teledyne LABS consolidates CETAC, Hanson, ISCO chromatography and pumps, Leeman Labs and Tekmar for Chromatography, GC Sample Prep, Elemental Analysis, Automated Liquid Handling, Pumping and Dissolution, Diffusion, Physical Tablet Testing. These complementary brands support our commitment to delivering innovative laboratory instruments that improve our environmental sustainability and quality of life.

Waters Corporation

Waters Corporation, a global leader in analytical instruments and software, has pioneered chromatography, mass spectrometry, and thermal analysis innovations serving the life, materials, and food sciences for more than 60 years. Waters operates directly in 35 countries, with products available in more than 100 countries.

Zeochem

Zeochem is a leading global manufacturer with 40 years experience in the production of high purity Chromatography Silica gels. With roots in Switzerland, we have a rich culture of environmental sustainability, customer service and high quality products.

Due to our consistently high quality and reproducible results Zeochem Chromatography Silica Gel has been used for decades in a wide variety of industries including pharmaceuticals, nutraceuticals, natural products, biopharmaceuticals, cosmetics, fine chemicals, food and beverages.

Zeochem silica gels can be relied on to ensure your separation process delivers high yields and purity, each time, every time.