PREP 2024

36th International Symposium on Preparative and Process Chromatography

 Philadelphia, PA, United States    May 28-31, 2024


1. Fundamentals of chromatography: purification paradigms and molecular mechanisms

2. Mechanistic and data-driven modelling: Digital Twins and AI/ML

The session will offer a forum to present new modeling approaches that can help to improve our understanding of separation phenomena, to accelerate the associated process development, and to increase the robustnes of manufacturing operations. Submissions may present new algorithms, faster parameter identification, or integrated simulation of sequences of unit operations.

3. Small molecules purification:  Chiral separations, high throughput screening, Impurities isolations

4. Complex purifications: Oligonucleotides, Peptides, Natural product, HPAPI, ADCs

5. Proteins: mono/multi-specific antibodies, therapeutic enzymes, gene-editing nucleases (CRISPR, TALEN, ZFN), blood factors, etc.

6. Gene and cell therapies: viral vectors (AAV, LVV, AdVs, etc.), non-viral vectors (exosomes, LNPs, etc.), si/mi-RNA, antisense oligonucleotides

7. Vaccines: recombinant vaccines, platform vaccines (viral and non-viral vectors, and virus-like particles), mRNA

8. Modern Downstream Bioprocessing: continuous purifications (multi-columns, flow-through operations), in/on/at-line PAT integration, industrial case studies, supercritical fluid chromatography

9. Sustainability in Separations

10. Natural Products